by Gable, J.E. et al.
Department of Chemistry and Biochemistry, University ofCalifornia at San Diego, La Jolla, California 92093, USA
Department of Chemistry and Biochemistry, University ofCalifornia at San Diego, La Jolla, California 92093, USA
These results support carpeting or toroidal pore mechanisms of membrane disruption by LL-37 and demonstrate that the combination of tryptophan mutants and sensitive spectroscopic tools may provide important molecular clues about antimicrobial action.
Biochemistry. 2009; 47:11264-72